For a muscle to contract, it needs to connect a neuron with muscle fibers. The union of a neuron with muscle fibers is called a motor unit or motor endplate. The muscle tissue that stimulates the neuron is called a motor neuron, and the neuromuscular union refers to the terminal axon of a motor neuron with the motor plate in the muscle. The axon contains many membrane-bound vesicles called synaptic vesicles.

For a muscle contraction, there must be a stimulation of the motor neuron that sends the signal and connects with the muscle fibers. ACh is then released into the vesicles. The process is regulated by the SNARE complex made up of three different proteins. ACh binds to the muscle fiber where AChRs are located and causes a series of changes that will ultimately involve the contraction of a muscle.

Muscle contractions are necessary for the mobility and proper functioning of our body, but if they involve an excess in their number and time, the skin will eventually generate expression wrinkles and easy lines, the two main causes of the loss of youthful appearance on the face.

The importance of knowing how this extracellular communication process develops lies in the ability of professionals to directly influence to reduce the adverse effects it has on the facial skin.

AGEPEEL is a biochemical peel developed by professionals that increases the regenerative capacity of the skin. It enhances hydration in the skin, increases the efficiency of regenerative cells in the cell maintenance process that proliferate giving rise to new fully functional cells, and achieves a more youthful skin.